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Thermo Fisher
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STATA Corporation
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Image Search Results
Journal: Nutrients
Article Title: Inhibition of Soluble Epoxide Hydrolase Is Protective against the Multiomic Effects of a High Glycemic Diet on Brain Microvascular Inflammation and Cognitive Dysfunction
doi: 10.3390/nu13113913
Figure Lengend Snippet: Hierarchical clustering of differentially expressed genes in hippocampal microvessels for the low glycemic diet (LGD) and the high glycemic diet (HGD) with and without soluble epoxide hydrolase inhibitor (sEHI). Hierarchical clustering of differentially expressed gene profiles in hippocampal microvessels of four experimental treatment groups: low glycemic diet (LGD), LGD with soluble epoxide hydrolase inhibitor (LGD+sEHI), high glycemic diet (HGD), and HGD with sEHI (HGD+sEHI). The data are shown for three biological replicates for each dietary group. Up-regulated genes are in red, and down-regulated genes are in blue. In the presence or absence of inhibitor, LGD groups had similar gene expression profiles while HGD groups had opposite gene expression profiles.
Article Snippet: Interaction of diet and inhibitor effects was performed using
Techniques: Gene Expression
Journal: Nutrients
Article Title: Inhibition of Soluble Epoxide Hydrolase Is Protective against the Multiomic Effects of a High Glycemic Diet on Brain Microvascular Inflammation and Cognitive Dysfunction
doi: 10.3390/nu13113913
Figure Lengend Snippet: Correlation of the high glycemic diet (HGD) with and without inhibitor to Alzheimer’s disease. Pearson correlation analysis between the genes modulated by the HGD vs LGD and the gene expression profiles observed in patients with Alzheimer’s disease extracted from GEO database number ( A ) GSE118553 and ( B ) GSE132903 . Correlation between genes modulated by the HGD+sEHI vs LGD and patients with Alzheimer’s disease extracted from GEO database number ( C ) GSE118553 and ( D ) GSE132903 .
Article Snippet: Interaction of diet and inhibitor effects was performed using
Techniques: Gene Expression